Seth was the fifth human, third son of Adam and Eve, and brother to Cain and the late Abel in the Book of Genesis. Seth took the place and role of his brother Abel, by continuing the worship of God through his ancestors. When he was 105 years old, his wife gave birth to Enos. He was the first of the "Messianic" or Christological line, being a direct ancestor to Jesus Christ.

As with all those mentioned in this first genealogy, he and his wife would have many children.